20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15249 | Estrogen receptor modulator 1 | Estrogen Receptor/ERR | |
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4... | |||
T78646 | Estrogen receptor antagonist 8 | Estrogen Receptor/ERR | |
Estrogen Receptor Antagonist 8 exhibits potent antagonistic activity against the estrogen receptor (ER), demonstrating effective anti-uterotrophic potential in vivo, with an EC50 value of 4.160 μM. | |||
T40893 | Estrogen receptor modulator 6 | ||
Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for... | |||
T11236 | Giredestrant tartrate | Estrogen receptor antagonist 1 | Estrogen Receptor/ERR , Others |
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure o... | |||
T11237 | Camizestrant | Estrogen receptor antagonist 2 | Estrogen Receptor/ERR |
Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1]. | |||
T4388 | PHTPP | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
PHTPP is a selective ERβ antagonist. | |||
TN1052 | Lindleyin | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens. | |||
T13768 | (+)-Medicarpin | Estrogen/progestogen Receptor | |
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium flo... | |||
T5S0543 | Isocurcumenol | Apoptosis , Estrogen Receptor/ERR , Reductase | |
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT). | |||
T7904 | SR 19881 | Estrogen/progestogen Receptor | |
SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay). | |||
T8984 | FLTX1 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
FLTX1 is a fluorescent derivative of Tamoxifen, designed to efficiently target and label intracellular Tamoxifen-binding sites (estrogen receptors) both under permeabilized and non-permeabilized conditions. Additionally,... | |||
T62952 | Estrogen receptor antagonist 5 | ||
Estrogen receptor antagonist 5 is a potent antagonist of the Estrogen receptor. Estrogen receptor (Estrogen receptor) is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and ... | |||
T63582 | Estrogen receptor antagonist 1 | ||
Estrogen receptor antagonist 1 is a potent antagonist of the estrogen receptor. Estrogen receptor antagonist 1 has shown research potential in breast cancer disease. | |||
T79064 | Estrogen receptor modulator 7 | Estrogen Receptor/ERR | |
Estrogen Receptor Modulator 7 is a potent modulator of estrogen receptors, utilized in cancer research [1]. | |||
T60293 | Estrogen receptor-IN-1 | ||
Estrogen receptor-IN-1 (compound 16) is an effective estrogen receptor (ER) inhibitor with IC 50 s of 13, 5μM for ERα and Erβ, respectively [1]. | |||
T63277 | Estrogen receptor antagonist 2 | ||
Estrogen receptor antagonist 2 is a selective down-regulator of estrogen receptor. Estrogen (E2) and estrogen alpha receptor (ERα) are important drivers of breast cancer development. estrogen receptor antagonist 2 has re... | |||
T63914 | Estrogen receptor antagonist 3 | ||
Estrogen receptor antagonist 3 is a potent degradation agent of the estrogen receptor (ER). Estrogen signalling systems play an important role in the regulation of cell growth, differentiation and apoptosis, and Estrogen... | |||
T63106 | Estrogen receptor antagonist 4 | ||
Estrogen Receptor Antagonist 4 is a potent inhibitor of the estrogen receptor (ER), crucial for regulating cell growth, differentiation, and apoptosis. This compound holds promise for cancer research[1]. | |||
T79109 | Estrogen receptor modulator 8 | Estrogen Receptor/ERR | |
Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells) and effectively hampers MCF-7 cell proliferation (IC50 = 0.... | |||
T39710 | ARV-471 | Vepdegestrant | Estrogen Receptor/ERR |
ARV-471 (Vepdegestrant) is a orally active Cereblon -based estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer. |